The Zazzy Substitution

1. The cat Sheldon first introduces as Dr. Robert Oppenheimer when in the cafeteria is not the same as the one in his apartment later.
2. When Leonard was contemplating getting a cat, he mentions he is looking at hypoallergenic to be sure to not upset Sheldon, yet Sheldon gets 25 cats that are clearly not hypoallergenic.

The Shiney Trinket Maneuver

Bernadette speaks about taking care of her brothers and sisters. In an earlier episode she claims her mother ran an illegal daycare.

The Loobenfeld Decay

In this episode Sheldon knocks 4 not his now neurotic OCD 3

The Wheaton Recurrence

In this episode Sheldon turns out to be a rather good bowler. In earlier episodes he and the others were unable to do well at Wii bowling. If Sheldon were as good a bowler as he is in this episode, he would have likely beeen able to do well at Wii bowling.

The Bad Fish Paradigm

When Sheldon and Penny are discussing her college degree in the laundry room there are several instances where Seldon begins to fold one item, scene cuts to Penny and when we go back to Sheldon a few seconds later he is folding different items.

The Adhesive Duck Deficiency

When Howard, Leonard and Raj are searching for asteroids, the coordinates are 34.48N, 118.31W. Close but not quite in a dark park. Also close to Vasquez Park instead of the likely more dark Angeles National Forest. Just .5 degrees west to 118.81W would have been a good spot also.

The Creepy Candy Coating Corollary

In "The Creepy Candy Coating Corollary" Sheldon is seen drinking Red Bull - full strength no diet. In other episodes - notably "The Work Song Nanocluster" Sheldon is deeply concerned about drinking caffeine and that it may lead to narcotics.